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1.
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12 p, 3.3 MB |
Spanish cohort of VEXAS syndrome : clinical manifestations, outcome of treatments and novel evidences about UBA1 mosaicism
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Mascaro, Jose Manuel (Hospital Clínic i Provincial de Barcelona) ;
Rodriguez-Pinto, Ignasi (Hospital Universitari MútuaTerrassa) ;
Poza, Gabriela (Hospital Universitario Virgen de la Arrixaca) ;
Mensa-Vilaro, Anna (Hospital Clínic i Provincial de Barcelona) ;
Fernández-Martín, Julián (Hospital Álvaro Cunqueiro) ;
Caminal-Montero, Luis (Instituto de Investigación Sanitaria del Principado de Asturias) ;
Espinosa, Gerard (Hospital Clínic i Provincial de Barcelona) ;
Hernández Rodríguez, José (Hospital Clínic i Provincial de Barcelona) ;
Diaz, Marina (Hospital Clínic i Provincial de Barcelona) ;
Rita-Marques, Joana (Hospital Universitari Vall d'Hebron) ;
Sanmartí, Raimon (Hospital Clínic i Provincial de Barcelona) ;
Castañeda, Santos (Universidad Autónoma de Madrid) ;
Colunga, Dolores (Hospital Universitario Central de Asturias) ;
Coto-Hernández, Rubén (Instituto de Investigación Sanitaria del Principado de Asturias) ;
Fanlo, Patricia (Hospital Universitario de Navarra) ;
Elejalde, Jose Ignacio (Hospital Universitario de Navarra) ;
Segundo, Bujan (Hospital Universitari Vall d'Hebron) ;
Figueras, Ignasi (Hospital Universitari de Bellvitge) ;
Marco, Francisco Manuel (Hospital General Universitario de Alicante Dr Balmis) ;
Andrés, Mariano (Universidad Miguel Hernández de Elche) ;
Suárez, Silvia (Hospital Valle del Nalón) ;
Gonzalez-Garcia, Andres (Hospital Universitario Ramón y Cajal) ;
Fustà-Novell, Xavier (Fundació Althaia de Manresa) ;
Garcia-Belando, Clara (Hospital Universitario Virgen de la Arrixaca) ;
Granados-Maturano, Ana (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Fernandez Figueras, Maria Teresa (Hospital Universitari General de Catalunya) ;
Quilis, Neus (Hospital Universitari de Vinalopo) ;
Orriols-Caba, Maria (Hospital comarcal Alt Penedès) ;
Gómez de la Torre, Ricardo (Hospital Universitario Central de Asturias) ;
Cid, María Cinta (Hospital Clínic i Provincial de Barcelona) ;
Espígol-Frigolé, Georgina (Hospital Clínic i Provincial de Barcelona) ;
Alvarez-Abella, Alba (Hospital Universitari MútuaTerrassa) ;
Labrador, Eztizen (Hospital San Pedro) ;
Rozman, Maria (Hospital Clínic i Provincial de Barcelona) ;
Lopez-Guerra, Monica (Hospital Clínic i Provincial de Barcelona) ;
Castillo, Paola (Hospital Clínic i Provincial de Barcelona) ;
Alamo-Moreno, Jose R (Hospital Clínic i Provincial de Barcelona) ;
Gonzalez-Roca, Eva (Hospital Clínic i Provincial de Barcelona) ;
Plaza, Susana (Hospital Clínic i Provincial de Barcelona) ;
Fabregat, Virginia (Hospital Clínic i Provincial de Barcelona) ;
Lara, Rocio (Hospital Clínic i Provincial de Barcelona) ;
Vicente-Rabaneda, Esther F (Universidad Autónoma de Madrid) ;
Tejedor Vaquero, Sonia (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Magri, Giuliana (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Bonet, Nuria (Universitat Pompeu Fabra) ;
Solis-Moruno, Manuel (Universitat Pompeu Fabra) ;
Cerutti, Andrea (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Fornas, Òscar (Universitat Pompeu Fabra) ;
Casals, Ferran (Universitat de Barcelona) ;
Yagüe, Jordi (Hospital Clínic i Provincial de Barcelona) ;
Aróstegui, Juan Ignacio (Hospital Clínic i Provincial de Barcelonaa) ;
Universitat Autònoma de Barcelona
The vacuoles, E1-enzyme, X linked, autoinflammatory and somatic (VEXAS) syndrome is an adult-onset autoinflammatory disease (AID) due to postzygotic UBA1 variants. To investigate the presence of VEXAS syndrome among patients with adult-onset undiagnosed AID. [...]
2023 -  10.1136/ard-2023-224460
Annals of the rheumatic diseases, Vol. 82 (september 2023) , p. 1594-1605
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2.
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11 p, 4.8 MB |
Methylome and transcriptome profiling of giant cell arteritis monocytes reveals novel pathways involved in disease pathogenesis and molecular response to glucocorticoids
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Estupiñán-Moreno, Elkyn (Instituto de Parasitología y Biomedicina "López-Neyra") ;
Ortiz-Fernández, Lourdes (Instituto de Parasitología y Biomedicina "López-Neyra") ;
Li, Tianlu (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Hernández-Rodríguez, José (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Ciudad, Laura (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Andrés-León, Eduardo (Instituto de Parasitología y Biomedicina "López-Neyra") ;
Terron-Camero, Laura Carmen (Instituto de Parasitología y Biomedicina "López-Neyra") ;
Prieto-González, Sergio (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Espígol-Frigolé, Georgina (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Cid, María Cinta (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Márquez, Ana (Instituto de Investigación Sanitaria de Granada) ;
Ballestar, Esteban (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Martín, Javier (Instituto de Parasitología y Biomedicina "López-Neyra")
Objectives Giant cell arteritis (GCA) is a complex systemic vasculitis mediated by the interplay between both genetic and epigenetic factors. Monocytes are crucial players of the inflammation occurring in GCA. [...]
2022 - 10.1136/annrheumdis-2022-222156
Annals of the rheumatic diseases, Vol. 81 Núm. 9 (january 2022) , p. 1290-1300
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3.
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9 p, 1.2 MB |
Development and validation of prediction models to estimate risk of primary total hip and knee replacements using data from the UK : two prospective open cohorts using the UK Clinical Practice Research Datalink
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Yu, Dahai (Keele University) ;
Jordan, Kelvin P.. (Keele University) ;
Snell, Kym I E. (Keele University) ;
Riley, Richard D. (Keele University) ;
Bedson, John (Keele University) ;
Edwards, John James (Keele University) ;
Mallen, Christian D. (Keele University) ;
Tan, Valerie (Keele University) ;
Ukachukwu, Vincent (Keele University) ;
Prieto-Alhambra, Daniel (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Walker, Christine (Keele University) ;
Peat, George (Keele University) ;
Universitat Autònoma de Barcelona
The ability to efficiently and accurately predict future risk of primary total hip and knee replacement (THR/TKR) in earlier stages of osteoarthritis (OA) has potentially important applications. We aimed to develop and validate two models to estimate an individual's risk of primary THR and TKR in patients newly presenting to primary care. [...]
2018 - 10.1136/annrheumdis-2018-213894
Annals of the rheumatic diseases, Vol. 78 (october 2018) , p. 91-99
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4.
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7 p, 424.0 KB |
Focused HLA analysis in Caucasians with myositis identifies significant associations with autoantibody subgroups
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Rothwell, Simon (University of Manchester) ;
Chinoy, Hector (Salford Royal NHS Foundation Trust) ;
Lamb, Janine A. (The University of Manchester) ;
Miller, Frederick W. (National Institute of Environmental Health Sciences) ;
Rider, Lisa G. (National Institute of Environmental Health Sciences) ;
Wedderburn, Lucy R. (University College London) ;
McHugh, Neil J. (University of Bath) ;
Mammen, Andrew L. (Johns Hopkins University School of Medicine) ;
Betteridge, Zoe E. (University of Bath) ;
Tansley, Sarah L. (Royal United Hospitals Bath NHS Foundation Trust) ;
Bowes, John (The University of Manchester) ;
Vencovský, Jiří (Charles University) ;
Deakin, Claire T. (University College London) ;
Dankó, Katalin (University of Debrecen) ;
Vidya, Limaye (Royal Adelaide Hospital) ;
Selva-O'Callaghan, Albert (Hospital Universitari Vall d'Hebron) ;
Pachman, Lauren M. (Northwestern University, Feinberg School of Medicine) ;
Reed, Ann M. (Duke University) ;
Molberg, Øyvind (University of Oslo) ;
Benveniste, Olivier (Pitié-Salpêtrière University Hospital) ;
Mathiesen, Pernille R. (University of Copenhagen) ;
Radstake, Timothy R. D. J. (Utrecht Medical Center) ;
Doria, Andrea (Division of Rheumatology, University of Padova) ;
De Bleecker, Jan (Ghent University) ;
Lee, Annette T. (The Feinstein Institute for Medical Research) ;
Hanna, M. G (University College London Institute of Neurology) ;
Machado, Pedro M. (London North West University Healthcare NHS Trust) ;
Ollier, William E. (Manchester Metropolitan University) ;
Gregersen, Peter K. (The Feinstein Institute for Medical Research) ;
Padyukov, Leonid (Karolinska University Hospital and Karolinska Institutet (Suècia)) ;
O'Hanlon, Terrance P. (National Institute of Environmental Health Sciences) ;
Cooper, Robert G. (University of Liverpool) ;
Lundberg, Ingrid E. (Karolinska University Hospital and Karolinska Institutet (Suècia)) ;
Universitat Autònoma de Barcelona
Idiopathic inflammatory myopathies (IIM) are a spectrum of rare autoimmune diseases characterised clinically by muscle weakness and heterogeneous systemic organ involvement. The strongest genetic risk is within the major histocompatibility complex (MHC). [...]
2019 - 10.1136/annrheumdis-2019-215046
Annals of the rheumatic diseases, Vol. 78 (may 2019) , p. 996-1002
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5.
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3 p, 273.6 KB |
Clinical features and outcomes of COVID-19 in patients with rheumatic diseases treated with biological and synthetic targeted therapies
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Sánchez Piedra, Carlos (Sociedad ESpañola de Reumatologia, Madrid) ;
Díaz Torne, César (Institut d'Investigació Biomèdica Sant Pau) ;
Manero, Javier (Hospital Universitario Miguel Servet (Saragossa)) ;
Pego Reigosa, José M. (Complexo Hospitalario Universitario de Vigo) ;
Rua Figueroa, Íñigo (Hospital Universitario de Gran Canaria Dr. Negrín) ;
Gonzalez-Gay, MA (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Gómez Reino, Juan (Complejo Hospitalario Universitario de Santiago de Compostela) ;
Álvaro Gracia, José M. (Hospital General Universitario Gregorio Marañón) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
2020 - 10.1136/annrheumdis-2020-217948
Annals of the Rheumatic Diseases, Vol. 79 Núm. 7 (5 06 2020) , p. 988-990
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6.
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8 p, 1.6 MB |
Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis : a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
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Hochberg, Marc C. (University of Maryland School of Medicine) ;
Martel-Pelletier, Johanne (Centre hospitalier de l'Université de Montréal) ;
Monfort, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Möller, Ingrid (Institut Poal de Reumatologia) ;
Castillo, Juan Ramón (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Arden, N. K (University of Oxford. Medical Science Division) ;
Berenbaum, Francis (Sorbonne University) ;
Blanco-García, F.J (Instituto de Investigación Biomédica de A Coruña) ;
Conaghan, Philip G. (Leeds Institute of Rheumatic and Musculoskeletal Medicine) ;
Domènech Carbó, Gemma (Universitat Autònoma de Barcelona. Facultat de Medicina) ;
Henrotin, Yves (Université de Liège. Faculté de Médecine. Unité de Recherche sur l'Os et le Cartilage) ;
Pap, Thomas (Universitätsklinikum Münster. Institut für Muskuloskelettale Medizin) ;
Richette, Pascal (Université Paris-Diderot) ;
Sawitzke, Allen (University of Utah School of Medicine) ;
du Souich, Patrick (Université de Montréal. Département de pharmacologie et physiologie) ;
Pelletier, Jean-Pierre (Centre de recherche du Centre hospitalier de l'Universite de Montreal)
To compare the efficacy and safety of chondroitin sulfate plus glucosamine hydrochloride (CS+GH) versus celecoxib in patients with knee osteoarthritis and severe pain. Double-blind Multicentre Osteoarthritis interVEntion trial with SYSADOA (MOVES) conducted in France, Germany, Poland and Spain evaluating treatment with CS+GH versus celecoxib in 606 patients with Kellgren and Lawrence grades 2-3 knee osteoarthritis and moderate-to-severe pain (Western Ontario and McMaster osteoarthritis index (WOMAC) score ≥301; 0-500 scale). [...]
2015 - 10.1136/annrheumdis-2014-206792
Annals of the rheumatic diseases, Vol. 75, issue 1 (Jan. 2016) , p. 37-44
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